The cell envelope glycoconjugates ofMycobacterium tuberculosis

Genotyping ofMycobacterium tuberculosis in China and Missing Links in the Chain of Ongoing Transmission of Tuberculosis

Worldwide, the epidemiology of tuberculosis varies widely from an uncommon disease refueled by immigration to highly endemic, with ongoing transmission as the driving force. Countries with the highest incidence rates are found in subSaharan Africa, whereas the highest absolute numbers of cases are recorded in India and China. The latter countries experience intermediate incidence rates, but hav...

Original Contribution Contribution of Seasonality in Transmission ofMycobacterium tuberculosis to Seasonality in Tuberculosis Disease: A Simulation Study

A seasonal rise in tuberculosis (TB) notifications has been confirmed in several studies. Here, we examined one hypothesis for its cause: increased transmission of TB during wintertime due to crowding. Seasonality analysis was performed on actual and simulated notifications of clustered TB cases, which are considered to be representative of recent transmission, diagnosed from 1993 to 2004 in th...

Cell Envelope Structure and Functions in Gram-negative Bacteria

The bacterial cell envelope.

Metabolic radiolabeling of animal cell glycoconjugates.

This unit describes metabolic labeling techniques that provide specific information about the structure, sequence, and distribution of the sugar chains of glycoconjugates. Although these techniques provide less information than complete sequencing of the sugar chains, the partial structural information derived is sufficient for many purposes. In the basic procedure presented in this unit, activ...